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cruises to south america

MSC Cruises to South America

MSC Cruises South America cruise vacations provide guests with a chance to experience a South American cruise in Italian style and elegance. MSC Cruises to South America introduce travelers to the sights and sounds of the region, from the serenity of private beaches to the bustling city life of Rio de Janeiro, and provide excellent ships that rival the finest hotels in Italy. Onboard MSC Cruise Line, passengers can relax in on-deck swimming pools, enjoy fine Italian 7-course meals, or enjoy an evening show for the family. With all MSC Cruises to South America, kids sail free, making this a valuable family choice.

Showing 126-150 of 172 results
7-night south america cruise
$862
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 21, 2026 from Rio de Janeiro, Brazil
Up to 1 deal
7-night south america cruise
$848
49% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Feb 22, 2026 from Santos, Brazil
Up to 1 deal
3-night south america cruise
$513
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 24, 2026 from Santos, Brazil
7-night south america cruise
$843
50% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 24, 2026 from Salvador, Brazil
7-night south america cruise
$868
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 24, 2026 from MACEIO
Up to 1 deal
7-night south america cruise
$744
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 25, 2026 from Salvador, Brazil
Up to 1 deal
7-night south america cruise
$873
50% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 25, 2026 from MACEIO
8-night south america cruise
$1,114
50% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Feb 25, 2026 from Buenos Aires, Argentina
8-night south america cruise
$1,600
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Feb 25, 2026 from Montevideo, Uruguay
Up to 1 deal
8-night south america cruise
$1,603
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Feb 26, 2026 from Buenos Aires, Argentina
Up to 1 deal
4-night south america cruise
$566
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 27, 2026 from Santos, Brazil
7-night south america cruise
$763
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 28, 2026 from Rio de Janeiro, Brazil
Up to 1 deal
7-night south america cruise
$868
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 28, 2026 from Santos, Brazil
7-night south america cruise
$798
49% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Mar 01, 2026 from Santos, Brazil
Up to 1 deal
3-night south america cruise
$493
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Mar 03, 2026 from Santos, Brazil
7-night south america cruise
$766
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Mar 03, 2026 from MACEIO
Up to 1 deal
7-night south america cruise
$874
50% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Mar 03, 2026 from Salvador, Brazil
7-night south america cruise
$766
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Mar 04, 2026 from Salvador, Brazil
Up to 1 deal
7-night south america cruise
$1,042
47% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Mar 04, 2026 from MACEIO
7-night south america cruise
$1,230
49% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Mar 05, 2026 from Buenos Aires, Argentina
Up to 1 deal
9-night south america cruise
$1,435
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Mar 05, 2026 from Montevideo, Uruguay
Up to 1 deal
4-night south america cruise
$595
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Mar 06, 2026 from Santos, Brazil
9-night south america cruise
$1,701
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Mar 06, 2026 from Buenos Aires, Argentina
Up to 1 deal
7-night south america cruise
$741
MSC Cruises – MSC Armonia
3.2 (19)
Departs Mar 07, 2026 from Rio de Janeiro, Brazil
Up to 1 deal
7-night south america cruise
$885
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Mar 07, 2026 from Santos, Brazil
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