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cruises to south america

MSC Cruises to South America

MSC Cruises South America cruise vacations provide guests with a chance to experience a South American cruise in Italian style and elegance. MSC Cruises to South America introduce travelers to the sights and sounds of the region, from the serenity of private beaches to the bustling city life of Rio de Janeiro, and provide excellent ships that rival the finest hotels in Italy. Onboard MSC Cruise Line, passengers can relax in on-deck swimming pools, enjoy fine Italian 7-course meals, or enjoy an evening show for the family. With all MSC Cruises to South America, kids sail free, making this a valuable family choice.

Showing 101-125 of 172 results
4-night south america cruise
$595
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 06, 2026 from Santos, Brazil
7-night south america cruise
$840
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 07, 2026 from Rio de Janeiro, Brazil
Up to 2 deals
7-night south america cruise
$889
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 07, 2026 from Santos, Brazil
Up to 1 deal
9-night south america cruise
$1,573
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Feb 07, 2026 from Montevideo, Uruguay
Up to 2 deals
7-night south america cruise
$808
49% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Feb 08, 2026 from Santos, Brazil
Up to 2 deals
9-night south america cruise
$1,970
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Feb 08, 2026 from Buenos Aires, Argentina
Up to 2 deals
3-night south america cruise
$513
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 10, 2026 from Santos, Brazil
7-night south america cruise
$833
60% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 10, 2026 from Salvador, Brazil
Up to 1 deal
7-night south america cruise
$928
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 10, 2026 from MACEIO
Up to 2 deals
7-night south america cruise
$958
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 11, 2026 from Salvador, Brazil
Up to 2 deals
7-night south america cruise
$993
50% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 11, 2026 from MACEIO
Up to 1 deal
7-night south america cruise
$857
48% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Feb 12, 2026 from Buenos Aires, Argentina
Up to 2 deals
4-night south america cruise
$595
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 13, 2026 from Santos, Brazil
7-night south america cruise
$910
54% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 14, 2026 from Rio de Janeiro, Brazil
Up to 2 deals
7-night south america cruise
$988
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 14, 2026 from Santos, Brazil
Up to 1 deal
7-night south america cruise
$938
49% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Feb 15, 2026 from Santos, Brazil
Up to 2 deals
9-night south america cruise
$1,573
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Feb 16, 2026 from Montevideo, Uruguay
Up to 2 deals
3-night south america cruise
$513
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 17, 2026 from Santos, Brazil
7-night south america cruise
$903
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 17, 2026 from MACEIO
Up to 2 deals
7-night south america cruise
$993
50% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 17, 2026 from Salvador, Brazil
Up to 1 deal
9-night south america cruise
$1,670
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Feb 17, 2026 from Buenos Aires, Argentina
Up to 2 deals
7-night south america cruise
$744
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 18, 2026 from Salvador, Brazil
Up to 2 deals
7-night south america cruise
$1,173
50% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 18, 2026 from MACEIO
Up to 1 deal
4-night south america cruise
$595
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 20, 2026 from Santos, Brazil
7-night south america cruise
$828
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 21, 2026 from Santos, Brazil
Up to 1 deal
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